심한 근관 감염에서의 항생제 선택
Antimicrobial choice of severe endodontic infection
조주연, 하정홍, 진명욱, 김영경, 김성교,
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조주연 ( Cho Ju-Yeon ) - 경북대학교 치의학전문대학원 치과보존학교실
하정홍 ( Ha Jung-Hong ) - 경북대학교 치의학전문대학원 치과보존학교실
진명욱 ( Jin Myoung-Uk ) - 경북대학교 치의학전문대학원 치과보존학교실
김영경 ( Kim Young-Kyung ) - 경북대학교 치의학전문대학원 치과보존학교실
김성교 ( Kim Sung-Kyo ) - 경북대학교 치의학전문대학원 치과보존학교실
KMID : 0362720140520070425
Abstract
Objectives : The purpose of our study was to evaluate penicillin as a still drug of choice for severe endodontic infection, by
analyzing the antimicrobial susceptibilities from endodontic infections with swelling to figure out appropriate antibiotics as
empirical treatment.
Materials and methods : This study involved 18 patients who attended for emergency treatment because of facial or periapical swelling associated with root canal infections. Identification and antimicrobial susceptibility test of each pathogen were performed by Vitek2 Systems (bioMerieux, Marcy l’Etoile, France).
Results : The most frequent bacteria was Streptococcus spp.(77%), and the resistance against penicillin was 35% in overall patients, followed by clindamycin and erythromycin (17%), which was much higher than previous studies.
Conclusions : In our study, the higher resistance made penicillin alone not to be chosen as the first antibiotic drug for severe endodontic infections. Combinations with other drug, penicillin with wider spectrum of activity, or changing to other antibiotics was considered while remembering the increased risk of resistant microorganism.
키워드
penicillin; antimicrobial; endodontic; infection; susceptibility
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